A new synthetic method of [Ru(2,2′:6′,2″-terpyridine)(2,2′-bipyridine)Cl]⁺ complexes using cis-[Ru(2,2′:6′,2″-terpyridine)(NCCH₃)₂Cl]⁺ as an intermediate and comparison…
A new method of synthesizing [Ru(terpy)(bpy)Cl]⁺ (terpy = 2,2′:6′,2″-terpyridine, bpy = 2,2′-bipyridine) complexes using the starting material cis-[Ru(terpy)(NCCH3)₂Cl](PF₆) is reported. The yields of four derivatives ([Ru(terpy)(NN)Cl](PF₆): NN = bpy, 1; 4,4′-(MeO)₂bpy, 2; 4,4′-(CF₃)₂bpy, 3; 2,2′-biquinoline, 4) with this method range from 58 to 94 % and are similar to or greater than a known reaction in which the starting material is [Ru(benzene)(NN)Cl](PF₆). However, the use of cis-[Ru(terpy)(NCCH₃)₂Cl](PF₆) results in lower levels of homoleptic Ru byproducts in the synthesis of 1 as compared to the use of [Ru(benzene)(bpy)Cl](PF₆) as determined by ¹H NMR spectroscopy. Additionally, a high-purity and gram-scale synthesis of cis-[Ru(terpy)(NCCH₃)₂Cl](PF₆) that does not use column chromatography is reported, in contrast to the original synthesis disclosed in the literature.
Tereniak, S. J.; Butler, B. J. A new synthetic method of [Ru(2,2′:6′,2″-terpyridine)(2,2′-bipyridine)Cl]⁺ complexes using cis-[Ru(2,2′:6′,2″-terpyridine)(NCCH₃)₂Cl]+ as an intermediate and comparison to a method using [Ru(benzene)(2,2′-bipyridine)Cl]⁺ intermediates, Inorg. Chim. Acta, 2025, 589, 122892, https://doi.org/10.1016/j.ica.2025.122892.
